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Researcher’s activity gives teens new insights into cancer research

Curtis McCloskey

PhD student Curtis McCloskey created an interactive activity to explain cancer immunotherapy research to Grade 11 and 12 students through Let’s Talk Science’s Outreach program. He hopes it will inspire more students to become the researchers of tomorrow.

Harnessing the body’s immune system to fight cancer is a new and complex field, but through his connections with Let’s Talk Science, PhD student Curtis McCloskey has adapted his research into an activity that teenagers can digest and understand.

“I always tell them ‘I’m going to teach you PhD-level cancer biology in an hour,’” said McCloskey, a student at The Ottawa Hospital and the University of Ottawa.

The cancer researcher in Dr. Barbara Vanderhyden’s lab has been a volunteer for Let’s Talk Science’s Outreach program for nine years. This program brings volunteers into classrooms to lead science, technology, engineering and math (STEM) activities.

McCloskey’s activity, “Cancer Biotherapeutics,” was funded by BioCanRx and inspired by his own work in immunotherapy. This relatively new field uses treatments that stimulate or restore the ability of the body’s immune system to fight cancer.

While immunotherapy is a complex topic, McCloskey has years of experience adapting information to suit the needs of different learners.

“I’ve taught a lot, and I’ve started to understand how kids learn. All this activity does is show them the differences between cancer cells and normal cells and how to exploit them,” he said.

In the first part of the activity, Grade 11 and 12 students learn all the ways cells can become cancerous.  In the second part, the students are divided into labs to develop different immune-based therapies to fight a rare form of cancer. The labs are given different clues to start out with. They can choose to keep their findings to themselves or share them with other teams, demonstrating the importance of collaboration in the research process. So far, more than 1,300 students across Canada have done the activity.

When he isn’t in a classroom, the PhD student is developing new therapies to treat ovarian cancer, and exploring new ways to use the immune system to fight this deadly cancer.

“When you go and teach kids, they’re always excited about the science. So very excited! For someone who works in research every day, it’s easy to get overwhelmed when experiments don’t work out as planned. But teaching kids always inspires and reminds you of why you got into science in the first place.”


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